Symptoms

Stethoscope and glass thermometer on a dark surface
Symptoms point clinicians toward an underlying diagnosis but are rarely a diagnosis on their own.
Infographic: body outline with four symptom groups
The hub groups symptoms by body system, from digestive and musculoskeletal to cardiopulmonary and neurologic, each linking to the conditions that produce it.
Semi-transparent body with several organs glowing
Fatigue alone can mean iron-deficiency anemia, hypothyroidism, depression, sleep apnea or any of a dozen other conditions.

Digestive

Liver, Bile & Pancreas

Musculoskeletal

Cardiopulmonary

Neurologic & Cognitive

Constitutional (Whole-Body)

Skin, Hair & Allergic

Urinary

Ear, Nose & Throat

Vascular & Circulatory

Symptoms are the body's signals that something has changed. They point clinicians toward an underlying diagnosis but are rarely a diagnosis on their own โ€” fatigue can mean iron-deficiency anemia, hypothyroidism, depression, sleep apnea, or any of a dozen other conditions, and the same is true of headache, bloating, joint pain, and most of the symptoms above. Each page describes a symptom, its common causes, when it warrants medical evaluation, and links to the conditions where it most often appears. The Symptom-to-Condition Reference Table links each symptom directly to the conditions that produce it.

Detailed pages exist for the symptoms above. The reference table further down covers a wider range, including symptoms without their own dedicated page yet.

Red Flags — Warning Signs by Urgency

Most symptoms can be evaluated by a primary-care physician within a few days. A handful warrant urgent care or emergency care today. The lists below describe the signs that hospitals and clinics treat as emergencies, as same-day problems, or as reasons for a check within a week.

Signs Treated as Emergencies (911)

Signs Usually Seen the Same Day

Signs Usually Checked Within a Week

Symptom-to-Condition Reference Table

A quick map from symptom to the conditions on this site that most often produce it. Where a symptom has its own page, the symptom name is linked. Otherwise, follow the links in the right-hand column to the relevant condition pages.

SymptomCommon Causes & Conditions
Abdominal pain Small intestinal bacterial overgrowth (SIBO) · irritable bowel syndrome (IBS) · Gallbladder disease · Pancreatitis · Peptic ulcer
Anxiety, panic episodes Anxiety · Graves' disease · postural orthostatic tachycardia syndrome (POTS) · mast cell activation syndrome (MCAS)
Back pain, chronic Ankylosing spondylitis · Fibromyalgia · Chronic pain · Tendinitis
Bloating, abdominal distension Small intestinal bacterial overgrowth · irritable bowel syndrome · Celiac disease · Gallbladder disease
Brain fog, cognitive haze Postural orthostatic tachycardia syndrome · mast cell activation syndrome · myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) · small intestinal bacterial overgrowth
Chest pain or pressure Coronary artery disease · Heart failure · Cardiomyopathy · gastroesophageal reflux disease (GERD)
Cold hands and feet Raynaud's disease · Peripheral artery disease · Hypothyroidism
Constipation Constipation-predominant irritable bowel syndrome (IBS-C) · IMO (methane small intestinal bacterial overgrowth) · Hypothyroidism
Cough, chronic Asthma · chronic obstructive pulmonary disease (COPD) · gastroesophageal reflux disease · Interstitial lung disease
Dark urine Hepatitis · Liver disease · Hemolytic anemia
Diarrhea, chronic Diarrhea-predominant irritable bowel syndrome (IBS-D) · Celiac disease · Crohn's disease · inflammatory bowel disease (IBD)
Dizziness, lightheadedness on standing Postural orthostatic tachycardia syndrome · Anemia · Sleep apnea · Diabetes
Dizziness, vertigo Meniere's disease · Multiple sclerosis · Vestibular migraine
Edema, swelling of legs or ankles Heart failure · Pleural effusion · Liver disease
Fatigue Anemia · Thyroid disorders · Hepatitis · myalgic encephalomyelitis/chronic fatigue syndrome · Sleep apnea
Fever Sepsis · Hepatitis · Endocarditis · Pneumonia · Influenza
Hair loss Alopecia · Hashimoto's thyroiditis · polycystic ovary syndrome (PCOS)
Headache, chronic Migraine · Hypertension · Anxiety
Heart palpitations Atrial fibrillation · Arrhythmia · postural orthostatic tachycardia syndrome · Graves' disease
Hives, flushing, urticaria Mast cell activation syndrome · Alpha-Gal syndrome · Allergies
Insomnia, sleep difficulty Sleep apnea · Anxiety · Depression · Hyperthyroidism
Itching (pruritus) Eczema · Liver disease (cholestasis) · Hepatitis
Jaundice (yellow skin or eyes) Hepatitis · Hepatitis B · Hepatitis C · Liver disease
Joint pain Rheumatology overview · Fibromyalgia · Tendinitis · Ankylosing spondylitis
Loss of appetite Hepatitis · Depression · Sepsis · Cancer
Memory problems, cognitive decline Alzheimer's disease · myalgic encephalomyelitis/chronic fatigue syndrome · Depression
Nausea and vomiting Migraine · Hepatitis · Pancreatitis · Gallbladder disease
Numbness, tingling, peripheral neuropathy Peripheral neuropathy · Multiple sclerosis · Diabetes · B12 deficiency
Pale stool Hepatitis · Liver disease · Gallbladder/biliary obstruction
Reflux, heartburn Gastroesophageal reflux disease · Peptic ulcer · small intestinal bacterial overgrowth
Shortness of breath Heart failure · Asthma · chronic obstructive pulmonary disease · Pulmonary embolism · Pleural effusion
Skin rash, chronic Eczema · Psoriasis · Rosacea · Dermatitis herpetiformis
Tremor Parkinson's disease · Graves' disease · Anxiety
Unintentional weight loss Cancer · Hyperthyroidism · Type 1 diabetes · inflammatory bowel disease
Urinary frequency, urgency Benign prostatic hyperplasia · Diabetes insipidus · Type 2 diabetes

How These Pages Are Organized

Each symptom page is meant for two readers:

  1. Someone trying to make sense of a new or persistent symptom. The Overview, Common Causes, and When to Seek Medical Care sections are the starting point — they describe what the symptom usually means, what tests a clinician might order, and when to escalate care.
  2. Someone trying to understand a symptom that comes with an existing diagnosis. The Mechanisms, Evaluation, and Connections sections explain how the symptom fits the broader condition and what overlapping diagnoses to consider.

None of this content replaces medical care. Every page links to peer-reviewed research with DOIs and to PubMed topic searches so you can read further or bring evidence to your appointments.

Connections

Symptoms โ€” scientific infographic poster