Neurology
Neurology focuses on disorders of the brain, spinal cord, and nervous system.
- Alzheimer's Disease — amyloid plaques, tau tangles, cholinesterase inhibitors
- Concussion — mild traumatic brain injury, coup-contrecoup, post-concussion syndrome, return-to-play
- Epilepsy — seizure classification, antiepileptic drugs, surgical options
- Migraine — cortical spreading depression, CGRP antibodies, triptans, gepants, magnesium/B2/CoQ10
- Multiple Sclerosis — demyelination, McDonald criteria, disease-modifying therapies
- Parkinson's Disease — dopamine depletion, levodopa, deep brain stimulation
- ALS (Lou Gehrig's Disease) — motor neuron degeneration, riluzole, edaravone
- Peripheral Neuropathy — nerve damage, diabetic neuropathy, pain management
- Huntington's Disease — CAG repeat expansion, chorea, genetic testing
- Myasthenia Gravis — neuromuscular junction, acetylcholine receptor antibodies, thymectomy
- ME/CFS — post-exertional malaise, pacing, the under-recognized multisystem neuroimmune disease
- POTS (postural orthostatic tachycardia syndrome) — full article plus 8 deep-dive guides on subtypes, tilt table test, salt & hydration, compression & exercise, medications, the POTS/MCAS/EDS triad, LDN, and vagus nerve & retraining
- MCAS (mast cell activation syndrome) — full article plus 8 deep-dive guides on mediators & symptom map, testing, low-histamine diet, H1/H2 blocker stacks, cromolyn & ketotifen, triggers & flares, hereditary α-tryptasemia, and natural stabilizers
Table of Contents
Key Research Papers
Foundational and recent peer-reviewed publications across the major neurology subspecialties — stroke, dementia, neurodegenerative disease, multiple sclerosis, epilepsy, headache, and movement disorders. Each citation links to the full text via DOI.
- The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue Plasminogen Activator for Acute Ischemic Stroke. New England Journal of Medicine. 1995;333(24):1581–1587.
- Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the Early Management of Patients with Acute Ischemic Stroke (AHA/ASA). Stroke. 2019;50(12):e344–e418.
- Berkhemer OA, Fransen PSS, Beumer D, et al. A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke (MR CLEAN). New England Journal of Medicine. 2015;372(1):11–20.
- Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus Warfarin in Patients with Atrial Fibrillation (RE-LY). New England Journal of Medicine. 2009;361(12):1139–1151.
- Granger CB, Alexander JH, McMurray JJV, et al. Apixaban versus Warfarin in Patients with Atrial Fibrillation (ARISTOTLE). New England Journal of Medicine. 2011;365(11):981–992.
- Sperling RA, Aisen PS, Beckett LA, et al. Toward Defining the Preclinical Stages of Alzheimer's Disease: Recommendations from the NIA-AA Workgroups on Diagnostic Guidelines for Alzheimer's Disease. Alzheimer's & Dementia. 2011;7(3):280–292.
- Sims JR, Zimmer JA, Evans CD, et al. Donanemab in Early Symptomatic Alzheimer Disease (TRAILBLAZER-ALZ 2). JAMA. 2023;330(6):512–527.
- van Dyck CH, Swanson CJ, Aisen P, et al. Lecanemab in Early Alzheimer's Disease (CLARITY-AD). New England Journal of Medicine. 2023;388(1):9–21.
- Postuma RB, Berg D, Stern M, et al. MDS Clinical Diagnostic Criteria for Parkinson's Disease. Movement Disorders. 2015;30(12):1591–1601.
- Thompson AJ, Banwell BL, Barkhof F, et al. Diagnosis of Multiple Sclerosis: 2017 Revisions of the McDonald Criteria. Lancet Neurology. 2018;17(2):162–173.
- Hauser SL, Bar-Or A, Comi G, et al. Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis (OPERA I and II). New England Journal of Medicine. 2017;376(3):221–234.
- Bensimon G, Lacomblez L, Meininger V. A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis. New England Journal of Medicine. 1994;330(9):585–591.
- Brown RH Jr, Al-Chalabi A. Amyotrophic Lateral Sclerosis. New England Journal of Medicine. 2017;377(2):162–172.
- Fisher RS, Acevedo C, Arzimanoglou A, et al. ILAE Official Report: A Practical Clinical Definition of Epilepsy. Epilepsia. 2014;55(4):475–482.
- Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders, 3rd Edition. Cephalalgia. 2018;38(1):1–211.
- Goadsby PJ, Reuter U, Hallström Y, et al. A Controlled Trial of Erenumab for Episodic Migraine. New England Journal of Medicine. 2017;377(22):2123–2132.
Live PubMed Searches
Live PubMed queries that update as new papers are indexed.
- PubMed: neurology clinical review
- PubMed: neurodegenerative disease mechanisms
- PubMed: Alzheimer's disease
- PubMed: Parkinson's disease
- PubMed: multiple sclerosis
- PubMed: epilepsy management
- PubMed: amyotrophic lateral sclerosis
- PubMed: Huntington's disease
- PubMed: peripheral neuropathy
- PubMed: myasthenia gravis
- PubMed: ME/CFS
- PubMed: POTS
Connections
- All Conditions
- Alzheimer's Disease
- Parkinson's Disease
- Multiple Sclerosis
- ALS
- Epilepsy
- Huntington's Disease
- Myasthenia Gravis
- Peripheral Neuropathy
- ME/CFS
- POTS
- MCAS
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