Trace Minerals

Sphalerite, the main ore of zinc
Sphalerite, the main ore of zinc
Malachite, a green copper mineral
Malachite, a green copper mineral

Trace Minerals on This Site

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Iron

Oxygen transport in haemoglobin. The world's commonest deficiency, and dangerous in excess because the body has no route to excrete it.

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Zinc

Insulin storage in the beta cell, immune function, wound healing; long-term high doses cause copper deficiency.

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Copper

Iron metabolism, connective tissue crosslinking and mitochondrial energy production — the mineral zinc supplementation most often displaces.

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Iodine

The element thyroid hormone is built from. Both deficiency and excess cause thyroid disease.

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Selenium

Glutathione peroxidases and the deiodinases that activate thyroid hormone; the therapeutic window is one of the narrowest here.

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Manganese

Superoxide dismutase in the mitochondrion, and bone matrix formation.

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Chromium

Proposed to amplify insulin signalling. The early enthusiasm has not held up under later review.

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♻️

Molybdenum

Cofactor for sulfite oxidase and xanthine oxidase; deficiency is essentially unknown on ordinary diets.

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Cobalt

Relevant to humans only as the cobalt atom at the centre of vitamin B12.

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🪨

Boron

Affects calcium, magnesium and vitamin D handling, and sex hormone levels; not formally essential, and hard to be short of.

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Silicon

Connective tissue and bone matrix formation; the evidence is suggestive rather than settled.

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⚖️

Strontium

Chemically follows calcium into bone, which is the basis of its use and of the caution around it.

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Vanadium

Genuinely insulin-mimetic in animal models, with a narrow gap between the doses that act and the doses that harm.

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Needed in under 100 mg a day, several of them in micrograms. Trace minerals are mostly catalytic rather than structural: they sit in the active site of an enzyme or at the centre of a hormone, so a small shortfall can stop a specific reaction while everything around it looks normal.

That is also why the margin matters. Several of these — iron, copper, selenium, iodine — have a genuinely narrow window between too little and too much, and the symptoms at both ends can resemble each other.

Connections