Pain & Allergy
This field focuses on chronic pain conditions and immune-mediated allergic disorders.
- Allergies — IgE-mediated reactions, anaphylaxis, immunotherapy
- Alpha-Gal Syndrome (tick-driven delayed allergy to mammalian meat) — full article plus 8 deep-dive guides on tick-origin science, complete foods list, cross-reactive meds, anaphylaxis plan, testing, restaurant & travel, tick prevention, and natural history
- Chronic Pain — nociceptive, neuropathic, nociplastic pain; multimodal management
- Anaphylaxis — severe allergic reactions, epinephrine, biphasic reactions, emergency management
- Complex Regional Pain Syndrome (CRPS) — formerly RSD; Budapest Criteria, mirror therapy, graded motor imagery, low-dose naltrexone
- Food Intolerance — lactose, histamine, elimination diets
- Mast Cell Activation Syndrome (MCAS) — mast cell mediator release triad, SIGHI criteria, tryptase testing, low-histamine diet, quercetin, EDS/POTS connection
- Cluster Headaches — episodic vs. chronic, high-flow oxygen, verapamil, galcanezumab, hypothalamic pathophysiology
- Migraine — aura, triptans, CGRP antagonists, prevention
- Neuropathic Pain — peripheral vs. central sensitization, DN4 tool, gabapentinoids, duloxetine, topical lidocaine, alpha-lipoic acid