Infectious Disease
Infectious disease focuses on illnesses caused by bacteria, viruses, fungi, and parasites, including diagnosis, treatment, and prevention strategies.
- Cellulitis (skin and soft tissue infection, SSTI classification, empiric antibiotics)
- Clostridioides difficile Infection (CDI, toxin A/B, fidaxomicin, FMT, IDSA/SHEA guidelines)
- Common Cold (rhinovirus, honest remedy evidence, zinc lozenges, red flags)
- Hepatitis (viral hepatitis overview, acute and chronic forms)
- Hepatitis B (HBV, serologic markers, tenofovir)
- Hepatitis C (HCV, direct-acting antivirals, SVR, cure)
- Herpes Simplex (HSV-1 and HSV-2, cold sores, asymptomatic shedding, suppressive therapy)
- HIV/AIDS (CD4 staging, ART regimens, PrEP, opportunistic infections)
- Lyme Disease (Borrelia burgdorferi, erythema migrans, doxycycline)
- Malaria (Plasmodium species, artemisinin-based therapy, chemoprophylaxis)
- Measles (Koplik spots, immune amnesia, vitamin A, MMR vaccination)
- Meningitis (bacterial and viral, CSF analysis, empiric antibiotics)
- Mononucleosis (Epstein-Barr virus, the kissing disease, splenomegaly, EBV and MS)
- Sepsis (Sepsis-3 criteria, SOFA/qSOFA, Surviving Sepsis Campaign)
- Strep Throat (Group A Strep, Centor criteria, penicillin, antibiotic stewardship)
- Tuberculosis (Mycobacterium tuberculosis, RIPE therapy, latent TB)
- Shingles (Herpes Zoster) (varicella-zoster reactivation, postherpetic neuralgia)
- Whooping Cough (Bordetella pertussis, the 100-day cough, DTaP/Tdap, macrolides, infant protection)
- Dengue Fever (DENV-1–4, Aedes aegypti, dengue shock syndrome, Qdenga vaccine)
- Typhoid Fever (Salmonella Typhi, XDR typhoid, typhoid conjugate vaccine, rose spots)
- Norovirus (winter vomiting bug, GII.4, fecal-oral transmission, oral rehydration)
- Hand-Foot-Mouth Disease (Enterovirus A71, CVA16, brainstem encephalitis, EV-A71 vaccine)
- Chickenpox (Varicella) (VZV primary infection, dew-drop vesicles, Oka vaccine, acyclovir within 24h, Reye's syndrome aspirin warning, VZV latency and shingles)
- Rocky Mountain Spotted Fever (Rickettsia rickettsii, Dermacentor tick, petechial rash wrists/ankles/palms/soles, endothelial vasculitis, doxycycline within 5 days, 5–7% mortality even treated)
- West Nile Virus (Culex mosquito, bird reservoir, 80% asymptomatic, West Nile fever, neuroinvasive disease — meningitis/encephalitis/acute flaccid paralysis, IgM ELISA serology, no antiviral, DEET prevention)
Key Research Papers
Foundational and recent peer-reviewed publications across major infectious disease topics — antimicrobial resistance, vaccines, sepsis, tuberculosis, HIV, hepatitis, vector-borne disease, and emerging pathogens. Each citation links to the full text via DOI.
- Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810.
- Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016. Intensive Care Medicine. 2017;43(3):304–377.
- Pai M, Behr MA, Dowdy D, et al. Tuberculosis. Nature Reviews Disease Primers. 2016;2:16076.
- INSIGHT START Study Group. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. New England Journal of Medicine. 2015;373(9):795–807.
- Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 Infection with Early Antiretroviral Therapy (HPTN 052). New England Journal of Medicine. 2011;365(6):493–505.
- Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clinical Infectious Diseases. 2007;44(Suppl 2):S27–S72.
- Lozano R, Naghavi M, Foreman K, et al. Global and Regional Mortality from 235 Causes of Death for 20 Age Groups in 1990 and 2010 (Global Burden of Disease 2010). Lancet. 2012;380(9859):2095–2128.
- Chambers HF, Deleo FR. Waves of Resistance: Staphylococcus aureus in the Antibiotic Era. Nature Reviews Microbiology. 2009;7(9):629–641.
- Steere AC, Strle F, Wormser GP, et al. Lyme Borreliosis. Nature Reviews Disease Primers. 2016;2:16090.
- Ghany MG, Morgan TR; AASLD-IDSA Hepatitis C Guidance Panel. Hepatitis C Guidance 2019 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection. Hepatology. 2020;71(2):686–721.
- Dondorp AM, Nosten F, Yi P, et al. Artemisinin Resistance in Plasmodium falciparum Malaria. New England Journal of Medicine. 2009;361(5):455–467.
- RTS,S Clinical Trials Partnership. Efficacy and Safety of RTS,S/AS01 Malaria Vaccine with or without a Booster Dose in Infants and Children in Africa: Final Results of a Phase 3, Individually Randomised, Controlled Trial. Lancet. 2015;386(9988):31–45.
- Henao-Restrepo AM, Camacho A, Longini IM, et al. Efficacy and Effectiveness of an rVSV-Vectored Vaccine in Preventing Ebola Virus Disease: Final Results from the Guinea Ring Vaccination, Open-Label, Cluster-Randomised Trial (Ebola Ça Suffit!) Lancet. 2017;389(10068):505–518.
- van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile. New England Journal of Medicine. 2013;368(5):407–415.
- McDonald LC, Gerding DN, Johnson S, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clinical Infectious Diseases. 2018;66(7):e1–e48.
- Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori Infection—the Maastricht V/Florence Consensus Report. Gut. 2017;66(1):6–30.
Live PubMed Searches
Live PubMed queries that update as new papers are indexed.
- PubMed: emerging infectious diseases
- PubMed: antimicrobial resistance
- PubMed: hospital-acquired infections
- PubMed: sepsis epidemiology
- PubMed: vaccine-preventable disease
- PubMed: zoonotic spillover
- PubMed: diagnostic stewardship
- PubMed: One Health
- PubMed: neglected tropical diseases
- PubMed: antibiotic stewardship
Connections
- Cellulitis
- Sepsis
- Meningitis
- Tuberculosis
- HIV/AIDS
- Hepatitis
- Lyme Disease
- Malaria
- Shingles
- Bacteria
- Immune Boosting
- Dengue Fever
- Typhoid Fever
- Norovirus
- Hand-Foot-Mouth Disease
- Chickenpox (Varicella)
- Rocky Mountain Spotted Fever
- West Nile Virus