Infectious Disease

Infectious disease focuses on illnesses caused by bacteria, viruses, fungi, and parasites, including diagnosis, treatment, and prevention strategies.

Cellulitis (skin and soft tissue infection, SSTI classification, empiric antibiotics)
Clostridioides difficile Infection (CDI, toxin A/B, fidaxomicin, FMT, IDSA/SHEA guidelines)
Hepatitis (viral hepatitis overview, acute and chronic forms)
Hepatitis B (HBV, serologic markers, tenofovir)
Hepatitis C (HCV, direct-acting antivirals, SVR, cure)
HIV/AIDS (CD4 staging, ART regimens, PrEP, opportunistic infections)
Lyme Disease (Borrelia burgdorferi, erythema migrans, doxycycline)
- Deep Dives: EM Rash Guide · Tick Bite First Aid · Testing Explained · Antibiotic Protocols · PTLDS & Chronic Lyme · Co-Infections · Neuroborreliosis · Prevention & Removal
Malaria (Plasmodium species, artemisinin-based therapy, chemoprophylaxis)
Meningitis (bacterial and viral, CSF analysis, empiric antibiotics)
Sepsis (Sepsis-3 criteria, SOFA/qSOFA, Surviving Sepsis Campaign)
Tuberculosis (Mycobacterium tuberculosis, RIPE therapy, latent TB)
Shingles (Herpes Zoster) (varicella-zoster reactivation, postherpetic neuralgia)

Key Research Papers

Foundational and recent peer-reviewed publications across major infectious disease topics — antimicrobial resistance, vaccines, sepsis, tuberculosis, HIV, hepatitis, vector-borne disease, and emerging pathogens. Each citation links to the full text via DOI.

Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810.
Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016. Intensive Care Medicine. 2017;43(3):304–377.
Pai M, Behr MA, Dowdy D, et al. Tuberculosis. Nature Reviews Disease Primers. 2016;2:16076.
INSIGHT START Study Group. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. New England Journal of Medicine. 2015;373(9):795–807.
Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 Infection with Early Antiretroviral Therapy (HPTN 052). New England Journal of Medicine. 2011;365(6):493–505.
Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clinical Infectious Diseases. 2007;44(Suppl 2):S27–S72.
Lozano R, Naghavi M, Foreman K, et al. Global and Regional Mortality from 235 Causes of Death for 20 Age Groups in 1990 and 2010 (Global Burden of Disease 2010). Lancet. 2012;380(9859):2095–2128.
Chambers HF, Deleo FR. Waves of Resistance: Staphylococcus aureus in the Antibiotic Era. Nature Reviews Microbiology. 2009;7(9):629–641.
Steere AC, Strle F, Wormser GP, et al. Lyme Borreliosis. Nature Reviews Disease Primers. 2016;2:16090.
Ghany MG, Morgan TR; AASLD-IDSA Hepatitis C Guidance Panel. Hepatitis C Guidance 2019 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection. Hepatology. 2020;71(2):686–721.
Dondorp AM, Nosten F, Yi P, et al. Artemisinin Resistance in Plasmodium falciparum Malaria. New England Journal of Medicine. 2009;361(5):455–467.
RTS,S Clinical Trials Partnership. Efficacy and Safety of RTS,S/AS01 Malaria Vaccine with or without a Booster Dose in Infants and Children in Africa: Final Results of a Phase 3, Individually Randomised, Controlled Trial. Lancet. 2015;386(9988):31–45.
Henao-Restrepo AM, Camacho A, Longini IM, et al. Efficacy and Effectiveness of an rVSV-Vectored Vaccine in Preventing Ebola Virus Disease: Final Results from the Guinea Ring Vaccination, Open-Label, Cluster-Randomised Trial (Ebola Ça Suffit!) Lancet. 2017;389(10068):505–518.
van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile. New England Journal of Medicine. 2013;368(5):407–415.
McDonald LC, Gerding DN, Johnson S, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clinical Infectious Diseases. 2018;66(7):e1–e48.
Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori Infection—the Maastricht V/Florence Consensus Report. Gut. 2017;66(1):6–30.